Web7 giu 2024 · HH-suite custom db with precomputed MSA. 1. Entering edit mode. 3.8 years ago. mnsp088 ▴ 100 Hi everyone. I am trying to create a custom database in HH-suite using a precomputed multiple sequence alignment (MSA) that I got from MUSCLE. WebThe HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). Documentation We provide an extensive user guide with many usage examples, frequently asked questions …
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WebThe HH-suite searches do many random file access and read operations. Therefore, it is recommended to store the databases of AlphaFold on a solid state drive (SSD) due to the significantly higher input/output speed (IOPS) compared to a traditional mechanical hard disk drive (HDD). WebThe HH-suite is an open-source software package for sensitive protein sequence searching based on the pairwise alignment of hidden Markov models (HMMs). Documentation We provide an extensive user guide with many usage examples, frequently asked questions and guides to build your own databases. Installation ecole chateaubriand lille
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Web14 nov 2015 · Here, we expanded the stability dataset by using protherm database recently updated in 2013 (Kumar et al., 2006). As with Hamelryck, we limited point mutants from VAL/ILE/LEU to ALA. These three residues were selected because mutations from small hydrophobic residues to ALA will not cause significant changes in polar interaction or in … Web28 mar 2024 · Some context - we are currently evaluating the possibility of moving one of our pipelines over to HH-suite. The pipeline is iterative and can involve a huge number of comparisons. We were hoping that hhalign would provide a drop-in replacement for our … Web25 feb 2024 · Background HH-suite is a widely used open source software suite for sensitive sequence similarity searches and protein fold recognition. It is based on pairwise alignment of profile Hidden... ecole chateaubriand marseille